PERBANDINGAN HASIL PEMERIKSAAN FINE NEEDLE ASPIRATION BIOPSY (FNAB) DENGAN GAMBARAN HISTOPATOLOGI PADA TUMOR TIROID

Abstract

The endocrine system is frequently impacted by thyroid cancers. Thyroid tumors account for 95% of all endocrine malignancies. Carcinomas, or malignancies, can occur in thyroid tumors. An FNAB examination is used to identify thyroid malignancies prior to surgery. The histological analysis of the surgical specimen is the gold standard for diagnosing thyroid tumors. This study compares the histological findings of thyroid cancers with the results of fine needle aspiration biopsy (FNAB). This study utilized an analytical observational design with a cross-sectional approach, involving 40 samples from secondary data. The data analysis revealed an average age of 45.48 (12.11) years, and the majority of cases were in females, with a total of 32 patients (80%). The FNAB examination results showed that 15 patients (37.5%) had malignant thyroid tumors, with the most common type being Papillary Tyroid Carcinoma in 13 patients (32,5%), and 25 patients (62.5%) had benign tumors, with the most common type being Adenomatous Goiter in 23 patients (57,5%). Histopathological findings indicated that 21 patients (52.5%) had malignant thyroid tumors, with Papillary Thyroid Carcinoma being the most common type in 14 patients (35%), and 19 patients (47.5%) had benign tumors, with Adenomatous Goiter being the most common type in 12 patients (30%). The sensitivity was 66.6%, specificity was 94.7%, accuracy was 80%, and the Kappa value was 0.605 with a p-value of 0.000, indicating good agreement according to the Cohen's Kappa value.